NRF2 Antikörper (pSer40)
Kurzübersicht für NRF2 Antikörper (pSer40) (ABIN5557501)
Target
Alle NRF2 (NFE2L2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pSer40
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Synthetic peptide derived from human Nrf2(S40), around 1-70aa (phospho S40).
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
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Andere Bezeichnung
- Nrf2
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Hintergrund
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Synonyms: NRF2, Nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2, HEBP1, Nuclear factor, erythroid derived 2, like 2, NFE2L2
Background: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
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Gen-ID
- 4780
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UniProt
- Q16236
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Pathways
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
Target
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