IRF7 Antikörper

Produktnummer ABIN5557323

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch IRF7 in WB und IF (cc). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IRF7 Antikörper (ABIN5557323)

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser IRF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Klon: 2A1

Produktdetails anti-IRF7 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant human IRF7 protein, around 200-300aa.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu IRF7

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Andere Bezeichnung: IRF7

Hintergrund:

Synonyms: signal transducers and activators of transduction 4, CIS4, HSPC060, SOCS4, SOCS6, SSI4, STAI4, STAT 4, STAT4, STATI4, Suppressor of cytokine signaling 6, STAT4_HUMAN.

Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011].

Gen-ID: 3665

UniProt: Q92985

Pathways: TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagie