GIP Antikörper (AA 104-136)

Produktnummer ABIN5535110

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GIP in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für GIP Antikörper (AA 104-136) (ABIN5535110)

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GIP Antikörper

Bindungsspezifität: AA 104-136

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-136 amino acids from the Central region of human GIPR.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GIP

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Andere Bezeichnung: GIP

Hintergrund: GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.

Molekulargewicht: 53 kDa

Gen-ID: 2696

UniProt: P48546

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism