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Glucagon Antikörper (N-Term)

Name: Glucagon Antikörper (N-Term)
SKU: ABIN5531264
Price: 694.38 EUR
Availability: InStock

GCG Reaktivität: Human, Maus WB, IHC (p), FACS Wirt: Kaninchen Polyclonal unconjugated

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with GCG Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (Glucagon Antikörper (N-Term))

IHC

Western blot analysis of GCG antibody in mouse bladder tissue lysates (35ug/lane) (Glucagon Antikörper (N-Term))

Flow cytometric analysis of HepG2 cells using GCG Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). (Glucagon Antikörper (N-Term))

FACS

3 Abbildungen

Produktnummer ABIN5531264

Datenblatt (PDF)

Target Alle Glucagon (GCG) Antikörper anzeigen

Glucagon (GCG)
Bindungsspezifität
16

15

8

7

7

6

5

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 25-54, N-Term
Reaktivität
126

52

48

15

7

6

4

3

3

3

2

2

2

1

1

1
Human, Maus
Wirt
91

31

9

4

1
Kaninchen
Passende Sekundärantikörper
Klonalität
94

42
Polyklonal
Konjugat
77

11

5

4

3

3

3

3

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Glucagon Antikörper ist unkonjugiert
Applikation
51

46

30

17

15

13

13

12

10

10

9

8

4

3

2

2

2

2

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen

This GCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human GCG.

Isotyp

Ig Fraction

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GCG Reaktivität: Human IHC, IF Wirt: Kaninchen Monoclonal unconjugated

anti-Glucagon (GCG) (AA 25-54), (N-Term) antibody
GCG Reaktivität: Human, Maus WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB19443 unconjugated

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anti-Glucagon (GCG) antibody
GCG Reaktivität: Human, Ratte, Maus ELISA, WB, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Glucagon (GCG) (AA 53-81), (N-Term) antibody
GCG Reaktivität: Human, Ratte, Maus IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Glucagon (GCG) (AA 23-180) antibody
GCG Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Glucagon (GCG) (AA 53-81) antibody
GCG Reaktivität: Human, Ratte, Maus ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

2 mg/mL

Buffer

Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target

Glucagon (GCG)

Andere Bezeichnung

GCG (GCG Produkte)

Hintergrund

GCG is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Molekulargewicht

21 kDa

Gen-ID

2641

UniProt

P01275

Pathways

Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling