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Glucagon Antikörper (C-Term)

GCG Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB19525 unconjugated
Produktnummer ABIN390769
  • Target Alle Glucagon (GCG) Antikörper anzeigen
    Glucagon (GCG)
    Bindungsspezifität
    • 16
    • 14
    • 10
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 119-148, C-Term
    Reaktivität
    • 118
    • 48
    • 43
    • 14
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 76
    • 30
    • 14
    • 4
    • 1
    Kaninchen
    Klonalität
    • 83
    • 41
    Polyklonal
    Konjugat
    • 76
    • 10
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Glucagon Antikörper ist unkonjugiert
    Applikation
    • 52
    • 50
    • 29
    • 15
    • 13
    • 13
    • 13
    • 12
    • 11
    • 11
    • 10
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Glucagon antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the C-terminal region of human Glucagon.
    Klon
    RB19525
    Isotyp
    Ig Fraction
  • Applikationshinweise
    IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P-Leica: 1:1000. FC: 1:25. IHC: 1:125
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    Glucagon (GCG)
    Andere Bezeichnung
    Glucagon (GCG Produkte)
    Synonyme
    GLP1 antikoerper, GLP2 antikoerper, GRPP antikoerper, GLP-1 antikoerper, Glu antikoerper, PPG antikoerper, GCG antikoerper, gcg-A antikoerper, gcg1 antikoerper, glucagon antikoerper, glucagon L homeolog antikoerper, GCG antikoerper, Gcg antikoerper, gcg.L antikoerper
    Hintergrund
    Glucagon is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
    Molekulargewicht
    20909
    Gen-ID
    2641
    NCBI Accession
    NP_002045
    UniProt
    P01275
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
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