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CTLA4 Antikörper (AA 36-161)

CTLA4 Reaktivität: Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5518903
  • Target Alle CTLA4 Antikörper anzeigen
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Bindungsspezifität
    • 16
    • 11
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 36-161
    Reaktivität
    • 96
    • 66
    • 34
    • 5
    • 4
    Maus, Ratte
    Wirt
    • 61
    • 52
    • 18
    • 12
    • 1
    • 1
    Kaninchen
    Klonalität
    • 89
    • 53
    • 2
    Polyklonal
    Konjugat
    • 67
    • 17
    • 13
    • 12
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CTLA4 Antikörper ist unkonjugiert
    Applikation
    • 87
    • 65
    • 51
    • 35
    • 19
    • 17
    • 14
    • 13
    • 10
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Cytotoxic T-lymphocyte protein 4(Ctla4) detection. Tested with WB, IHC-P, ELISA in Mouse,Rat.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Cytotoxic T-lymphocyte protein 4(Ctla4) detection. Tested with WB, IHC-P, ELISA in Mouse,Rat.
    Gene Name: cytotoxic T-lymphocyte-associated protein 4
    Protein Name: Cytotoxic T-lymphocyte protein 4
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E. coli-derived mouse CTLA4 recombinant protein (Position: E36-D161). Mouse CTLA4 shares 67.5% amino acid (aa) sequence identity with human CTLA4.
    Isotyp
    IgG
    Top Product
    Discover our top product CTLA4 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse

    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Andere Bezeichnung
    Ctla4 (CTLA4 Produkte)
    Synonyme
    CTLA-4 antikoerper, CTLA4 antikoerper, CD152 antikoerper, Cd152 antikoerper, Ctla-4 antikoerper, Ly-56 antikoerper, CD antikoerper, CELIAC3 antikoerper, GRD4 antikoerper, GSE antikoerper, IDDM12 antikoerper, sCTLA4 antikoerper, cytotoxic T-lymphocyte associated protein 4 antikoerper, cytotoxic T-lymphocyte-associated protein 4 antikoerper, CTLA4 antikoerper, Ctla4 antikoerper
    Hintergrund
    CTLA-4(Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that down regulates the immune system. It is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Blockade of CTLA4 expression in vitro augmented HIV-specific CD4-positive T-cell function.

    Synonyms: Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, Ctla4, Cd152
    Gen-ID
    12477
    UniProt
    P09793
    Pathways
    Cancer Immune Checkpoints
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