AKR1C1 Antikörper (C-Term)

Produktnummer ABIN5514650

Der Kaninchen Polyklonal anti-AKR1C1 Antikörper (ABIN5514650) detektiert spezifisch AKR1C1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für AKR1C1 Antikörper (C-Term) (ABIN5514650)

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AKR1C1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: AKR1C1 Antibody - C-terminal region

Sequenz: LVAYSALGSH REEPWVDPNS PVLLEDPVLC ALAKKHKRTP ALIALRYQLQ

Produktmerkmale: This is a rabbit polyclonal antibody against AK1C1. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human AK1C1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76080-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu AKR1C1

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Andere Bezeichnung: AKR1C1

Hintergrund:

Background Information: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Gene Name: aldo-keto reductase family 1 member C1

Alternative Symbols: C9, DD1, DDH, DDH1, H-37, HBAB, MBAB, HAKRC, DD1/DD2, 2-ALPHA-HSD, 20-ALPHA-HSD

Protein Name: aldo-keto reductase family 1 member C1

Molekulargewicht: 35kDa

Gen-ID: 1645

NCBI Accession: NP_001344

UniProt: Q04828

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process