Complement Factor B Antikörper (N-Term)

Produktnummer ABIN5514558

Produktdetails anti-Complement Factor B Antikörper

Target: Complement Factor B (CFB)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schaf, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Complement Factor B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NGAGYCSNPG IPIGTRKVGS QYRLEDSVTY HCSRGLTLRG SQRRTCQEGG

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CFAB. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CFAB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Complement Factor B

Target: Complement Factor B (CFB)

Andere Bezeichnung: CFAB (CFB Produkte)

Synonyme: AHUS4 antikoerper, BF antikoerper, BFD antikoerper, CFAB antikoerper, FB antikoerper, FBI12 antikoerper, GBG antikoerper, H2-Bf antikoerper, PBF2 antikoerper, bf antikoerper, Bf-1 antikoerper, Brre-Bf antikoerper, zgc:114032 antikoerper, Bf antikoerper, Sp152 antikoerper, bfb-A antikoerper, Bf B antikoerper, LOC397725 antikoerper, bf/c2 antikoerper, CFB antikoerper, AI195813 antikoerper, AI255840 antikoerper, B antikoerper, C2 antikoerper, Fb antikoerper, Da1-24 antikoerper, complement factor B antikoerper, complement factor B S homeolog antikoerper, complement factor B L homeolog antikoerper, CFB antikoerper, cfb antikoerper, bf antikoerper, cfb.S antikoerper, cfb.L antikoerper, bf/c2 antikoerper, LOC100555981 antikoerper, Cfb antikoerper

Hintergrund: CFAB is a factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B- lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

Alias Symbols: CFB, BF, BFD,

Protein Interaction Partner: FN1, LAMC3, RPA2, ALB, CFP, C3,

Protein Size: 764

Gen-ID: 629

NCBI Accession: NP_001701

UniProt: P00751

Pathways: Komplementsystem, Proton Transport, Ribonucleoside Biosynthetic Process