Complement Factor B Antikörper (Center)

Produktnummer ABIN391536

Der Kaninchen Polyklonal anti-Complement Factor B Antikörper (Klon RB18685) (ABIN391536) detektiert spezifisch Complement Factor B in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Complement Factor B Antikörper (Center) (ABIN391536)

Target: Complement Factor B (CFB)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Complement Factor B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB18685

Produktdetails anti-Complement Factor B Antikörper

Bindungsspezifität: AA 395-422, Center

Spezifität: This BF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401~431 amino acids from the Center region of human BF.

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This BF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-422 AA from the Central region of human BF.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB = 1:1000, IHC (p) = 1:50-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Complement Factor B

Target: Complement Factor B (CFB)

Andere Bezeichnung: Complement Factor B

Hintergrund: BF is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
Synonyms: Complement factor B, C3/C5 convertase, Properdin factor B, Glycine-rich beta glycoprotein, GBG, PBF2, Complement factor B Ba fragment, Complement factor B Bb fragment, BFD, BF, CFB

Molekulargewicht: 85533 DA

Gen-ID: 629

UniProt: P00751

Pathways: Komplementsystem, Proton Transport, Ribonucleoside Biosynthetic Process