Complement Factor B Antikörper (AA 469-494)

Produktnummer ABIN652979

Produktdetails anti-Complement Factor B Antikörper

Target: Complement Factor B (CFB)

Bindungsspezifität: AA 469-494

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Complement Factor B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 469-494 amino acids from the Central region of human CFB.

Klon: RB21500

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Complement Factor B

Target: Complement Factor B (CFB)

Andere Bezeichnung: CFB (CFB Produkte)

Synonyme: AHUS4 antikoerper, BF antikoerper, BFD antikoerper, CFAB antikoerper, FB antikoerper, FBI12 antikoerper, GBG antikoerper, H2-Bf antikoerper, PBF2 antikoerper, bf antikoerper, Bf-1 antikoerper, Brre-Bf antikoerper, zgc:114032 antikoerper, Bf antikoerper, Sp152 antikoerper, bfb-A antikoerper, Bf B antikoerper, LOC397725 antikoerper, bf/c2 antikoerper, CFB antikoerper, AI195813 antikoerper, AI255840 antikoerper, B antikoerper, C2 antikoerper, Fb antikoerper, Da1-24 antikoerper, complement factor B antikoerper, complement factor B S homeolog antikoerper, complement factor B L homeolog antikoerper, CFB antikoerper, cfb antikoerper, bf antikoerper, cfb.S antikoerper, cfb.L antikoerper, bf/c2 antikoerper, LOC100555981 antikoerper, Cfb antikoerper

Hintergrund: CFB encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.

Molekulargewicht: 85533

Gen-ID: 629

NCBI Accession: NP_001701

UniProt: P00751

Pathways: Komplementsystem, Proton Transport, Ribonucleoside Biosynthetic Process