DEPTOR Antikörper (AA 111-301)
Kurzübersicht für DEPTOR Antikörper (AA 111-301) (ABIN5027150)
Target
Alle DEPTOR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 111-301
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Aufreinigung
- Protein A Chromatography
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Immunogen
- A partial length recombinant DEPTOR protein (amino acids 111-301) was used as the immunogen for this antibody.
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Isotyp
- IgG
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anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 56-170) antibody
DEPTOR Reaktivität: Human, Maus, Ratte WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 1-220) antibodyDEPTOR Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 1-409) antibodyDEPTOR Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 86-120) antibodyDEPTOR Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB57442 unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 3-38) antibodyDEPTOR Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB57441 unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 1-409) antibodyDEPTOR Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 1-409) antibodyDEPTOR Reaktivität: Human ELISA Wirt: Maus Monoclonal 5B3 unconjugated
anti-DEP Domain Containing mTOR-Interacting Protein (DEPTOR) (AA 230-280) antibodyDEPTOR Reaktivität: Human, Ratte, Pferd, Affe WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 2-4 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- DEPTOR (DEP Domain Containing mTOR-Interacting Protein (DEPTOR))
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Andere Bezeichnung
- DEPTOR/DEPDC6
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Hintergrund
- DEPTOR is an mTOR inhibitor whose expression is negatively regulated by mTOR. DEPTOR expression is required to maintain PI3K and Akt activation and to inhibit apoptosis. DEPTOR is expressed in different microvascular ECs (endothelial cells). It plays a key role in maintaining stem cell pluripotency by limiting mTOR activity in undifferentiated embryonic stem cells (ESCs). It is overexpressed in RPMI-8226 human multiple myeloma cells, and plays an important role in maintaining cell survival.
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Molekulargewicht
- 46 kDa
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Gen-ID
- 64798
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UniProt
- Q8TB45
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Pathways
- PI3K-Akt Signalweg, RTK Signalweg, Regulation of Cell Size, BCR Signaling, Warburg Effekt
Target
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