TLR4 Antikörper (N-Term)
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- Target Alle TLR4 Antikörper anzeigen
- TLR4 (Toll-Like Receptor 4 (TLR4))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TLR4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects CD284 / TLR4 at N-term.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human
- Aufreinigung
- Ion exchange chromatography
- Immunogen
- TLR4 antibody was raised against a peptide corresponding to 15 amino acids near the amino-terminus of human TLR4.
- Isotyp
- IgG
- Top Product
- Discover our top product TLR4 Primärantikörper
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- Applikationshinweise
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ELISA. Western blot: 2 to 5 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS containing 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- TLR4 (Toll-Like Receptor 4 (TLR4))
- Andere Bezeichnung
- CD284 / TLR4 (TLR4 Produkte)
- Synonyme
- ARMD10 antikoerper, CD284 antikoerper, TLR-4 antikoerper, TOLL antikoerper, Lps antikoerper, Ly87 antikoerper, Ran/M1 antikoerper, Rasl2-8 antikoerper, toll like receptor 4 antikoerper, toll-like receptor 4 antikoerper, TLR4 antikoerper, Tlr4 antikoerper
- Hintergrund
- Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kappaB (4-6). Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis (7).Synonyms: Toll-like receptor 4
- Gen-ID
- 7099
- NCBI Accession
- NP_612564
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteine
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