CARD9 Antikörper

Produktnummer ABIN499537

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CARD9 in WB, IF und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CARD9 Antikörper (ABIN499537)

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARD9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-CARD9 Antikörper

Spezifität: CARD9 antibody was raised against a synthetic peptide corresponding to amino acids 521 to 536 of human CARD9 The sequence is different from that of rat origin by two amino acids.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Human CARD9 Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: CARD9 antibody can be used for detection of CARD9 at 0.5 to 1 μg/mL. A bandat approximately 59 kDa can be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu CARD9

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Andere Bezeichnung: CARD9

Hintergrund: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10 (1). CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-kappaB. CARD9 is an upstream activator of BCL-10 and NF-kappaB signaling.Synonyms: Caspase recruitment domain-containing protein 9

Gen-ID: 64170

NCBI Accession: NP_434700

UniProt: Q9H257

Pathways: Activation of Innate immune Response