CARD9 Antikörper (Middle Region)
Kurzübersicht für CARD9 Antikörper (Middle Region) (ABIN2787348)
Target
Alle CARD9 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- CARD9 Antibody - middle region
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Sequenz
- ALHQEQVLRN PHDAGLSSGE PPEKERRRLK ESFENYRRKR ALRKMQKGWR
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Homologie
- Dog: 92%, Horse: 86%, Human: 100%, Mouse: 90%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CARD9. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CARD9
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57704-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))
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Andere Bezeichnung
- CARD9
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Hintergrund
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Background Information: The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.
Gene Name: Caspase recruitment domain family, member 9
Alternative Symbols: CANDF2, hCARD9
Protein Name: Caspase recruitment domain-containing protein 9
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Molekulargewicht
- 62kDa
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Gen-ID
- 64170
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NCBI Accession
- NP_434700
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UniProt
- Q9H257
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Pathways
- Activation of Innate immune Response
Target
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