TLR4 Antikörper (AA 669-698)
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- Target Alle TLR4 Antikörper anzeigen
- TLR4 (Toll-Like Receptor 4 (TLR4))
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Bindungsspezifität
- AA 669-698
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TLR4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), ELISA
- Kreuzreaktivität (Details)
- Expected species reactivity: Bovine, Pig, Hamster
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A portion of amino acids 669-698 from the human protein was used as the immunogen for this TLR4 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product TLR4 Primärantikörper
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- Applikationshinweise
- Titration of the TLR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the TLR4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- TLR4 (Toll-Like Receptor 4 (TLR4))
- Andere Bezeichnung
- TLR4 (TLR4 Produkte)
- Synonyme
- ARMD10 antikoerper, CD284 antikoerper, TLR-4 antikoerper, TOLL antikoerper, Lps antikoerper, Ly87 antikoerper, Ran/M1 antikoerper, Rasl2-8 antikoerper, toll like receptor 4 antikoerper, toll-like receptor 4 antikoerper, TLR4 antikoerper, Tlr4 antikoerper
- Hintergrund
- TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.
- UniProt
- O00206
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteine
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