RIPK3 Antikörper (AA 489-518)

Produktnummer ABIN3032450

Der Kaninchen Polyklonal Anti-RIPK3-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, RIPK3 in Proben von Human und Maus zu detektieren.

Kurzübersicht für RIPK3 Antikörper (AA 489-518) (ABIN3032450)

Target: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIPK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-RIPK3 Antikörper

Bindungsspezifität: AA 489-518

Aufreinigung: Purified

Immunogen: A portion of amino acids 489-518 from the human protein was used as the immunogen for this RIPK3 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the RIPK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the RIPK3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu RIPK3

Target: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Andere Bezeichnung: RIPK3

Hintergrund: RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

UniProt: Q9Y572

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades