RIPK3 Antikörper (N-Term)

Produktnummer ABIN2777333

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-RIPK3 Antikörper (ABIN2777333) detektiert spezifisch RIPK3 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Schwein, Pferd und Hund.

Kurzübersicht für RIPK3 Antikörper (N-Term) (ABIN2777333)

Target: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIPK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RIPK3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: RIPK3 Antibody - N-terminal region

Sequenz: GGSQSGTGSG EPGGTLGYLA PELFVNVNRK ASTASDVYSF GILMWAVLAG

Homologie: Cow: 79%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against RIPK3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RIPK3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31513-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RIPK3 Antikörper (ABIN2777333)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Details zu RIPK3

Target: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Andere Bezeichnung: RIPK3

Hintergrund:

Background Information: RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

Gene Name: Receptor-interacting serine-threonine kinase 3

Alternative Symbols: RIP3

Protein Name: Receptor-interacting serine/threonine-protein kinase 3

Molekulargewicht: 57 kDa

Gen-ID: 11035

NCBI Accession: NP_006862

UniProt: Q9Y572

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades