ULK1 Antikörper (pSer556)
Kurzübersicht für ULK1 Antikörper (pSer556) (ABIN3029448)
Target
Alle ULK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer556
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Aufreinigung
- Antigen affinity purified
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Immunogen
- This phospho-ULK1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS556 of human ULK1.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the phospho-ULK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:200,Dot blot: 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the phospho-ULK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ULK1 (Unc-51 Like Kinase 1 (ULK1))
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Andere Bezeichnung
- ULK1
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Hintergrund
- Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells (By similarity). [UniProt]
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UniProt
- O75385
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Pathways
- Regulation of Cell Size, Autophagie
Target
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