BRAF Antikörper (pSer445)
Kurzübersicht für BRAF Antikörper (pSer445) (ABIN3029547)
Target
Alle BRAF Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer445
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Verwendungszweck
- Phospho-BRAF Antibody (pS445)
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Chicken
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Aufreinigung
- Antigen affinity
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Immunogen
- This phospho-BRAF antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS445 of human BRAF.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the phospho-BRAF antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the phospho-BRAF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
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Andere Bezeichnung
- BRAF
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Hintergrund
- BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
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UniProt
- P15056
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Pathways
- MAPK Signalweg, RTK Signalweg, Neurotrophin Signalübertragung, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagie
Target
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