c-MET Antikörper (Catalytic Domain)

Produktnummer ABIN3031757

Der Maus Monoklonal Anti-c-MET-Antikörper wurde für WB, ELISA, IHC und IF validiert. Er ist geeignet, c-MET in Proben von Human und Maus zu detektieren.

Kurzübersicht für c-MET Antikörper (Catalytic Domain) (ABIN3031757)

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser c-MET Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon: 4AT44

Produktdetails anti-c-MET Antikörper

Bindungsspezifität: Catalytic Domain

Aufreinigung: Purified

Immunogen: This MET antibody was produced from mice immunized with purified recombinant protein encoding the catalytic domain of human MET/HGFR.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Titration of the MET antibody (HGFR) may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:100,IHC (Paraffin): 1:25-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the MET antibody (HGFR) and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu c-MET

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Andere Bezeichnung: MET (HGFR)

Hintergrund: The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P08581

Pathways: RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor