IRAK4 Antikörper (AA 422-449)
Kurzübersicht für IRAK4 Antikörper (AA 422-449) (ABIN3028767)
Target
Alle IRAK4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 422-449
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Verwendungszweck
- Irak4 Antibody
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 422-449 from the mouse protein was used as the immunogen for this Irak4 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the Irak4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Aliquot the Irak4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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Andere Bezeichnung
- Irak4
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Hintergrund
- Irak4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1 (By similarity).
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UniProt
- Q8R4K2
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Pathways
- NF-kappaB Signalweg, TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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