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HIF1A Antikörper (AA 1-30)

Name: HIF1A Antikörper (AA 1-30)
SKU: ABIN3031283
Price: 673.5 EUR
Availability: InStock

HIF1A Reaktivität: Human, Hamster WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of HIF1 alpha antibody and CHO lysate (HIF1A Antikörper (AA 1-30))

Fluorescent confocal image of HeLa cell stained with HIF1 alpha antibody at 1:25. (HIF1A Antikörper (AA 1-30))

HIF1 alpha antibody IHC analysis in formalin fixed and paraffin embedded lung carcinoma. (HIF1A Antikörper (AA 1-30))

IHC

5 Abbildungen

Produktnummer ABIN3031283

Datenblatt (PDF)

Target Alle HIF1A Antikörper anzeigen

HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
Bindungsspezifität
20

16

16

14

8

7

6

6

6

5

4

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-30
Reaktivität
161

93

85

23

23

20

13

11

9

8

7

6

5

5

4

2

2

2

2

2

1

1

1

1

1

1
Human, Hamster
Wirt
151

53

5
Kaninchen
Passende Sekundärantikörper
Klonalität
157

52
Polyklonal
Konjugat
104

24

16

6

5

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser HIF1A Antikörper ist unkonjugiert
Applikation
166

77

60

53

50

39

39

26

26

25

12

8

7

7

3

3

3

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität (Details)

Expected species reactivity: Bovine

Aufreinigung

Purified

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for this HIF1 alpha antibody.

Isotyp

Ig Fraction

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anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) antibody
HIF1A Reaktivität: Human WB, IHC, ELISA, ICC Wirt: Maus Monoclonal 1A3 unconjugated

anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 216-336) antibody
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anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 329-530) antibody
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HIF1A Reaktivität: Human, Maus WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Titration of the HIF-1 alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Aliquot the HIF1 alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target

HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))

Andere Bezeichnung

HIF1 alpha (HIF1A Produkte)

Hintergrund

Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This protein encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas.

UniProt

Q16665

Pathways

Positive Regulation of Peptide Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Transition Metal Ion Homeostasis, Tube Formation, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals, Warburg Effekt