GSK3 beta Antikörper (AA 30-59)
Kurzübersicht für GSK3 beta Antikörper (AA 30-59) (ABIN3031094)
Target
Alle GSK3 beta (GSK3b) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 30-59
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Kreuzreaktivität (Details)
- Expected species reactivity: Human, Rat
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A portion of amino acids 30-59 from the mouse protein was used as the immunogen for this Gsk3b antibody.
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Isotyp
- Ig Fraction
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anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 4-34), (N-Term) antibody
GSK3b Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB03816 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) antibodyGSK3b Reaktivität: Human, Maus WB, IF, IP Wirt: Maus Monoclonal 2E6-D6-C12 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (N-Term) antibodyGSK3b Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 4-34) antibodyGSK3b Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 2-33) antibodyGSK3b Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal RB56641 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 362-395) antibodyGSK3b Reaktivität: Ratte WB Wirt: Kaninchen Polyclonal RB56577 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 2-33), (pSer9) antibodyGSK3b Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB56641 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) antibodyGSK3b Reaktivität: Human, Maus, Ratte WB, IF, IP, ICC Wirt: Maus Monoclonal 2E6-D6-C12 unconjugated
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Applikationshinweise
- Titration of the Gsk3b antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Gsk3b antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
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Andere Bezeichnung
- Gsk3b
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Hintergrund
- Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1 (By similarity).
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UniProt
- Q9WV60
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Pathways
- WNT Signalweg, Hedgehog Signalweg, Fc-epsilon Rezeptor Signalübertragung, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagie, BCR Signaling, Warburg Effekt
Target
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