Der Kaninchen Polyklonal anti-CD11b Antikörper wird verwendet zum Nachweis von CD11b in Proben von Human. Er wurde validiert für FACS, IHC, WB und ELISA.
ITGAM
Reaktivität: Human
ICC, ELISA
Wirt: Maus
Monoclonal
3A10H5
unconjugated
Applikationshinweise
Titration of the CD11b antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS pH 7.4 with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the CD11b antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
CD11b (ITGAM)
(Integrin alpha M (ITGAM))
Andere Bezeichnung
CD11b
Hintergrund
CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.