BAD Antikörper (AA 53-81)
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- Target Alle BAD Antikörper anzeigen
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
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Bindungsspezifität
- AA 53-81
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BAD Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A portion of amino acids 53-81 from the human protein was used as the immunogen for this Bad antibody.
- Top Product
- Discover our top product BAD Primärantikörper
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- Applikationshinweise
- Titration of the Bad antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the Bad antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
- Andere Bezeichnung
- Bad (BAD Produkte)
- Hintergrund
- Bad is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein.
- UniProt
- Q92934
- Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, Apoptose, Fc-epsilon Rezeptor Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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