p21 Antikörper (AA 126-154)
Kurzübersicht für p21 Antikörper (AA 126-154) (ABIN3031125)
Target
Alle p21 (CDKN1A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 126-154
-
Aufreinigung
- Antigen affinity purified
-
Immunogen
- A portion of amino acids 126-154 from the mouse protein was used as the immunogen for this anti-p21 antibody.
-
Isotyp
- Ig Fraction
-
-
anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (AA 43-142) antibody
CDKN1A Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) antibodyKO Validated CDKN1A Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (AA 65-164) antibodyCDKN1A Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 2F1 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) antibodyCDKN1A Reaktivität: Human, Non-Human Primate ELISA, IHC (p), ICC Wirt: Maus Monoclonal WA-1 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (AA 1-164) antibodyCDKN1A Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (AA 1-100) antibodyCDKN1A Reaktivität: Synthetic WB, IHC (f) Wirt: Kaninchen Monoclonal unconjugated Recombinant Antibody
anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (AA 21-100) antibodyCDKN1A Reaktivität: Human, Maus, Ratte, Schaf WB, ELISA, FACS, IHC (p), IF (p), IF (cc), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (AA 117-146), (C-Term) antibodyCDKN1A Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB33282 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (AA 134-164), (C-Term) antibodyCDKN1A Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB3180 unconjugated
anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (pThr145) antibodyCDKN1A Reaktivität: Human WB, IHC (p), DB Wirt: Kaninchen Polyclonal RB07512 unconjugated
-
-
Applikationshinweise
- Titration of the anti-p21 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the anti-p21 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
-
Andere Bezeichnung
- p21
-
Hintergrund
- May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity).
-
UniProt
- P39689
-
Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Zellzyklus, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagie
Target
-
