MAPK14 Antikörper

Produktnummer ABIN4953278

Der Maus Monoklonal anti-MAPK14 Antikörper (Klon 5A1-C5-F11) (ABIN4953278) detektiert spezifisch MAPK14 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Primate.

Kurzübersicht für MAPK14 Antikörper (ABIN4953278)

Target: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Reaktivität: Human, Maus, Ratte, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAPK14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 5A1-C5-F11

Produktdetails anti-MAPK14 Antikörper

Aufreinigung: Protein G affinity

Immunogen: A human recombinant partial protein was used as the immunogen for this MAPK14 / p38 MAPK antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the p38 MAPK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

Lagerung: -20 °C

Informationen zur Lagerung: Store the p38 MAPK antibody at -20°C.

Details zu MAPK14

Target: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Andere Bezeichnung: p38 MAPK / MAPK14

Hintergrund: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each.

UniProt: Q16539

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagie, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteine