Der Maus Monoklonal anti-FADD Antikörper (Klon 5A3-C7-G9) (ABIN4953248) detektiert spezifisch FADD in WB und IP.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
The stated application concentrations are suggested starting points. Titration of the FADD antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In PBS with 50 % glycerol and 0.03 % ProClin 300
Konservierungsmittel
ProClin
Vorsichtsmaßnahmen
This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store the FADD antibody at -20oC.
Target
FADD
(Fas (TNFRSF6)-Associated Via Death Domain (FADD))
Andere Bezeichnung
FADD
Hintergrund
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. [UniProt]