Der Maus Monoklonal anti-FADD Antikörper (Klon 5A3-C7-G9) (ABIN4953248) detektiert spezifisch FADD in WB und IP.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
FADD
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB40884
unconjugated
Applikationshinweise
The stated application concentrations are suggested starting points. Titration of the FADD antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,Immunoprecipitation: suitable
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
Lagerung
-20 °C
Informationen zur Lagerung
Store the FADD antibody at -20°C.
Target
FADD
(Fas (TNFRSF6)-Associated Via Death Domain (FADD))
Andere Bezeichnung
FADD
Hintergrund
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. [UniProt]