FADD Antikörper

Produktnummer ABIN4953248

Dieses Anti-FADD-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von FADD in WB und IP. Geeignet für Human.

Kurzübersicht für FADD Antikörper (ABIN4953248)

Target: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FADD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Klon: 5A3-C7-G9

Produktdetails anti-FADD Antikörper

Aufreinigung: Protein G affinity

Immunogen: A human recombinant protein was used as the immunogen for this FADD antibody.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the FADD antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,Immunoprecipitation: suitable

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

Lagerung: -20 °C

Informationen zur Lagerung: Store the FADD antibody at -20°C.

Details zu FADD

Target: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Andere Bezeichnung: FADD

Hintergrund: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. [UniProt]

UniProt: Q13158

Pathways: Apoptose, TLR Signalweg, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades