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CD14 Antikörper (AA 65-327)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD14 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN4950462

Kurzübersicht für CD14 Antikörper (AA 65-327) (ABIN4950462)

Target

Alle CD14 Antikörper anzeigen
CD14

Reaktivität

  • 286
  • 49
  • 38
  • 26
  • 23
  • 22
  • 22
  • 22
  • 19
  • 18
  • 17
  • 14
  • 14
  • 13
  • 12
  • 9
  • 7
  • 7
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 248
  • 67
  • 25
  • 3
  • 3
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 281
  • 65
  • 2
Polyklonal

Konjugat

  • 151
  • 32
  • 25
  • 19
  • 15
  • 8
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD14 Antikörper ist unkonjugiert

Applikation

  • 239
  • 122
  • 101
  • 69
  • 63
  • 52
  • 28
  • 24
  • 20
  • 14
  • 11
  • 7
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 37
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-327

    Aufreinigung

    Antigen affinity

    Immunogen

    Amino acids 65-327 of human CD14 were used as the immunogen for the CD14 antibody.

    Isotyp

    IgG
  • Applikationshinweise

    Optimal dilution of the CD14 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    Lagerung

    -20 °C

    Informationen zur Lagerung

    After reconstitution, the CD14 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target

    CD14

    Andere Bezeichnung

    CD14

    Hintergrund

    CD14 is a single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. This gene is located at bands 5q23-q31. The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns.

    UniProt

    P08571

    Pathways

    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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