CD11b Antikörper

Produktnummer ABIN490173

Produktdetails anti-CD11b Antikörper

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reaktivität: Human, Maus, Kaninchen, Primate

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD11b Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Blocking Reagent (BR), Neutralization (Neut)

Spezifität: The rat monoclonal antibody M1/70 detects CD11b (integrin alphaM subunit), a type I transmembrane protein mainly expressed on monocytes/macrophages, granulocytes and NK-cells, which associates with CD18 to form Mac-1 integrin that plays important role in cell-cell interactions.

Aufreinigung: Protein G purified

Endotoxin-Niveau: Low Endotoxin

Immunogen: B10 mouse spleen cells enriched for T cells.

Type of Immunogen: Cells

Klon: M1-70

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Approved: Block, Flo, Func, IHC, IHC-Fr, IP, Neut

Usage: Flow Cytometry: Recommended dilution - 1 μg/mL. Functional Application: In vitro blocking of CD11b. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Azide-free PBS,  pH 7.4, 0.2 micron filter sterilized

Konservierungsmittel: Azide free

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze/thaw cycles. This low endotoxin solution contains no preservative, handle under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 2-8°C. For long-term storage aliquot and store at -20°C. Avoid freeze/thaw cycles. This low endotoxin solution contains no preservative
handle under aseptic conditions.

Details zu CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung: ITGAM / CD11b (ITGAM Produkte)

Synonyme: CD11b/CD18 antikoerper, CR3 antikoerper, CR3A antikoerper, Cd11b antikoerper, F730045J24Rik antikoerper, Ly-40 antikoerper, MAC1 antikoerper, Mac-1 antikoerper, Mac-1a antikoerper, CD11B antikoerper, MAC-1 antikoerper, MAC1A antikoerper, MO1A antikoerper, SLEB6 antikoerper, C3bi antikoerper, integrin subunit alpha M antikoerper, integrin alpha M antikoerper, integrin, alpha M (complement component 3 receptor 3 subunit) antikoerper, integrin alpha-M antikoerper, ITGAM antikoerper, Itgam antikoerper, LOC100351865 antikoerper

Hintergrund: Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

Gen-ID: 3684

UniProt: P11215

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation