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FOXO1 Antikörper (AA 242-655)

Der Maus Monoklonal anti-FOXO1 Antikörper (Klon 7h3) (ABIN400650) detektiert spezifisch FOXO1 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Produktnummer ABIN400650
692,31 €
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
Lieferung nach: Deutschland
Lieferung in 16 Werktagen

Kurzübersicht für FOXO1 Antikörper (AA 242-655) (ABIN400650)

Target

Alle FOXO1 Antikörper anzeigen
FOXO1 (Forkhead Box O1 (FOXO1))

Reaktivität

  • 266
  • 200
  • 176
  • 51
  • 33
  • 25
  • 18
  • 13
  • 9
  • 8
  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 244
  • 25
  • 1
Maus

Klonalität

  • 211
  • 59
Monoklonal

Konjugat

  • 126
  • 12
  • 9
  • 8
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 2
  • 2
Dieser FOXO1 Antikörper ist unkonjugiert

Applikation

  • 223
  • 91
  • 91
  • 78
  • 76
  • 61
  • 60
  • 41
  • 40
  • 19
  • 7
  • 4
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

7h3
  • Bindungsspezifität

    • 29
    • 23
    • 22
    • 21
    • 18
    • 16
    • 16
    • 16
    • 10
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 242-655

    Spezifität

    This antibody recognizes Human FKHR.

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human.

    Produktmerkmale

    Synonyms: Forkhead Box Protein O1, FOXO1, FKHR, Forkhead Box Protein O1A, Forkhead inRhabdomyosarcoma

    Aufreinigung

    Protein G Chromatography.

    Immunogen

    Fusion protein containing the region encoding aa 242-655 of Human FOXO1A expressed inE. coli.

    Isotyp

    IgG1
  • Applikationshinweise

    Western Blot: 0.1-2.0 μg/mL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.2 containing no preservatives.

    Konservierungsmittel

    Without preservative

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    Haltbarkeit

    12 months
  • Target

    FOXO1 (Forkhead Box O1 (FOXO1))

    Andere Bezeichnung

    FOXO1A

    Hintergrund

    FOXO1A (FKHR or ForkHead in Rhabdomyosarcoma) is a 70 kDa protein which is a member of a subfamily of the forkhead homeotic gene family of transcription factors. Recent studies have shown that this protein can act as either a coactivator or a corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the C terminus of the FOXO1A protein. The specific function of the gene has not yet been determined, however, it may play a role in myogenic growth and differentiation. Chromosomal aberrations involving FOXO1A are a cause of rhabdomyosarcoma 2 (RMS2), also known as alveolar rhabdomyosarcoma.Synonyms: FKHR, FOXO1, Forkhead Box Protein O1, Forkhead Box Protein O1A, Forkhead in Rhabdomyosarcoma

    Gen-ID

    2308

    UniProt

    Q12778

    Pathways

    PI3K-Akt Signalweg, Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
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