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PIK3R2 Antikörper (AA 442-471)

Der Kaninchen Polyklonal Anti-PIK3R2-Antikörper wurde für WB validiert. Er ist geeignet, PIK3R2 in Proben von Human zu detektieren.
Produktnummer ABIN392582

Kurzübersicht für PIK3R2 Antikörper (AA 442-471) (ABIN392582)

Target

Alle PIK3R2 (PI3K p85b) Antikörper anzeigen
PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

Reaktivität

  • 112
  • 55
  • 26
  • 17
  • 14
  • 4
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 106
  • 6
Kaninchen

Klonalität

  • 96
  • 16
Polyklonal

Konjugat

  • 49
  • 8
  • 8
  • 7
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser PIK3R2 Antikörper ist unkonjugiert

Applikation

  • 88
  • 45
  • 35
  • 16
  • 13
  • 13
  • 7
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)

Klon

RB13727
  • Bindungsspezifität

    • 15
    • 9
    • 8
    • 8
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 442-471

    Homologie

    B, M, Rat

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This PIK3R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-471 amino acids from human PIK3R2.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

    Andere Bezeichnung

    PIK3R2

    Hintergrund

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The family has been classified into 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. PIK3R2 binds to activated Protein Tyrosine Kinases, which are phosphorylated, through its SH2 domain, and acts as an adaptor, mediating the association of the P110 catalytic unit to the plasma membrane.

    Molekulargewicht

    81545

    Gen-ID

    5296

    NCBI Accession

    NP_005018

    UniProt

    O00459

    Pathways

    VEGF Signaling, BCR Signaling
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