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JNK Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-JNK-Antikörper wurde für WB, IF und IHC (p) validiert. Er ist geeignet, JNK in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN391724

Kurzübersicht für JNK Antikörper (C-Term) (ABIN391724)

Target

Alle JNK (MAPK8) Antikörper anzeigen
JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

Reaktivität

  • 206
  • 117
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  • 40
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  • 20
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  • 9
  • 5
  • 3
  • 2
  • 2
  • 1
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Human

Wirt

  • 190
  • 25
  • 3
  • 1
Kaninchen

Klonalität

  • 176
  • 43
Polyklonal

Konjugat

  • 114
  • 15
  • 12
  • 10
  • 9
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
Dieser JNK Antikörper ist unkonjugiert

Applikation

  • 167
  • 82
  • 55
  • 49
  • 40
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  • 2
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  • 1
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  • 1
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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB0922
  • Bindungsspezifität

    • 55
    • 28
    • 19
    • 16
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    • 11
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    • 6
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    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 358-389, C-Term

    Homologie

    Rat

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This MAPK8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-389 amino acids from the C-terminal region of human MAPK8.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    IF: 1:10~50. WB: 1:2000. IHC-P: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Li, Sahbaie, Zheng, Ritchie, Peltz, Mogil, Clark: "Expression genetics identifies spinal mechanisms supporting formalin late phase behaviors." in: Molecular pain, Vol. 6, pp. 11, (2010) (PubMed).

  • Target

    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

    Andere Bezeichnung

    JNK1

    Hintergrund

    JNK1 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation.

    Molekulargewicht

    48296

    Gen-ID

    5599

    NCBI Accession

    NP_001265476, NP_002741, NP_620634, NP_620637

    UniProt

    P45983

    Pathways

    MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteine
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