BRAF Antikörper (pThr598)
Kurzübersicht für BRAF Antikörper (pThr598) (ABIN389791)
Target
Alle BRAF Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- pThr598
-
Homologie
- C, M, B, Rat
-
Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
Immunogen
- This BRAF Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T598 of human BRAF.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- DB: 1:500
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
Haltbarkeit
- 6 months
-
-
- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
-
Andere Bezeichnung
- BRAF
-
Hintergrund
- BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
-
Molekulargewicht
- 84437
-
Gen-ID
- 673
-
NCBI Accession
- NP_004324
-
UniProt
- P15056
-
Pathways
- MAPK Signalweg, RTK Signalweg, Neurotrophin Signalübertragung, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagie
Target
-