Zitiert in 1 Publikation.
Der Kaninchen Polyklonal anti-SMAD4 Antikörper (Klon RB07971) (ABIN389658) detektiert spezifisch SMAD4 in WB, ELISA, IF, IHC (p) und DB.
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Arjunan, Gnanaprakasam, Ananth, Romej, Rajalakshmi, Prasad, Martin, Gurusamy, Thangaraju, Bhutia, Ganapathy: "Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis." in: Investigative ophthalmology & visual science, Vol. 57, Issue 4, pp. 1612-9, (2016) (PubMed).
Target
SMAD4
(SMAD Family Member 4 (SMAD4))
Andere Bezeichnung
SMAD4
Hintergrund
Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.