Der Kaninchen Polyklonal anti-FADD Antikörper (Klon RB6864) (ABIN389559) detektiert spezifisch FADD in WB.
Dieser Antikörper reagiert spezifisch mit Proben aus Maus.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This mouse FADD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S191 of mouse FADD.
FADD
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB40884
unconjugated
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Target
FADD
(Fas (TNFRSF6)-Associated Via Death Domain (FADD))
Andere Bezeichnung
FADD
Hintergrund
FADD is an apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.