c-MET Antikörper (Catalytic Domain)

Produktnummer ABIN387745

Dieses Maus Monoklonal-Antikörper erkennt spezifisch c-MET in WB und IF. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für c-MET Antikörper (Catalytic Domain) (ABIN387745)

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser c-MET Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: 4AT247

Produktdetails anti-c-MET Antikörper

Bindungsspezifität: Catalytic Domain

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This monoclonal antibody is generated from mice immunized with purified recombinant protein encoding the catalytic domain of human Met.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: IF: 1:100. WB: 1:1000. WB: 1:100~500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu c-MET

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Andere Bezeichnung: MET/HGFR

Hintergrund: The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 155541

Gen-ID: 4233

NCBI Accession: NP_000236, NP_001120972

UniProt: P08581

Pathways: RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor