c-MET Antikörper (pTyr1234, pTyr1235)
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- Target Alle c-MET (MET) Antikörper anzeigen
- c-MET (MET) (Met Proto-Oncogene (MET))
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Bindungsspezifität
- pTyr1234, pTyr1235
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Reaktivität
- Human, Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser c-MET Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- Immunogen
- This monoclonal antibody is generated from mice immunized with a KLH conjugated synthetic peptide corresponding to sequences in Tyr1234/1235 region of human Met and residues both Tyr1234 and Tyr1235 are phosphorylated.
- Klon
- 6AT1877
- Isotyp
- IgG1
- Top Product
- Discover our top product MET Primärantikörper
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- Applikationshinweise
- WB: 1:100~500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- c-MET (MET) (Met Proto-Oncogene (MET))
- Andere Bezeichnung
- MET/HGFR (MET Produkte)
- Hintergrund
- The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
- 155541
- Gen-ID
- 4233
- NCBI Accession
- NP_000236, NP_001120972
- UniProt
- P08581
- Pathways
- RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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