CD11b Antikörper

Produktnummer ABIN380068

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD11b in IHC und IHC (fro). Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für CD11b Antikörper (ABIN380068)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD11b Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: OX-42

Produktdetails anti-CD11b Antikörper

Spezifität: CD11b/c. OX-42 recognizes three major polypeptides of 160  kDa, 103  kDa and 95  kDa and a minor 133  kDa protein under non-reducing conditions. Under reducing conditions two major peptides of 163  kDa and 100  kDa and a minor 135  kDa peptide are detected. Antigen distribution: Isolated cells: OX-42 shows a similar reaction pattern to OX-41 on various isolated cells but stains bronchial lavage cells to a lesser degree. OX-42 inhibits complement mediated rosettes. Tissue sections: OX-42 is a most suitable marker for the identification of microglial cells and Kupffer cells. It also stains dendritic cells strongly. Only a subpopulation of alveolar macrophages is recognised. Specificity: Rat: granulocytes, macrophages, microglial cells. Other species: not tested

Aufreinigung: Purified

Immunogen: Peritoneal macrophages

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-Fr (1:100 - 1:200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS  pH 7.2, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.

Details zu CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung: CD11b + C

Hintergrund: Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

Gen-ID: 3684

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation