CD11b Antikörper (PE)
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- Target Alle CD11b (ITGAM) Antikörper anzeigen
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD11b Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- Mouse/Human/Rhesus/Baboon/Rabbit CD11b, Mr 170 kDa
- Produktmerkmale
- Rat Anti-Mouse CD11b-PE
- Aufreinigung
- Purified
- Immunogen
- C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes
- Klon
- M1-70
- Isotyp
- IgG2b
- Top Product
- Discover our top product ITGAM Primärantikörper
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- Applikationshinweise
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, and AF488 conjugates 1 g/106 cells PE, APC, SPRD, CY5, PE/CY7, APC/CY7, PACBLU, AF647 and AF700 0.3 g/106 cells conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Kommentare
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In vitro and in vivo blocking
- Probenmenge
- 2 mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.1 mg/mL
- Buffer
- 0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C
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- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Andere Bezeichnung
- CD11b (ITGAM Produkte)
- Synonyme
- CD11b/CD18 antikoerper, CR3 antikoerper, CR3A antikoerper, Cd11b antikoerper, F730045J24Rik antikoerper, Ly-40 antikoerper, MAC1 antikoerper, Mac-1 antikoerper, Mac-1a antikoerper, CD11B antikoerper, MAC-1 antikoerper, MAC1A antikoerper, MO1A antikoerper, SLEB6 antikoerper, C3bi antikoerper, integrin subunit alpha M antikoerper, integrin alpha M antikoerper, integrin, alpha M (complement component 3 receptor 3 subunit) antikoerper, integrin alpha-M antikoerper, ITGAM antikoerper, Itgam antikoerper, LOC100351865 antikoerper
- Hintergrund
- CD11b, the integrin α M subunit, combines with CD18, the integrin β 2 subunit, to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1/CD54. Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. Mac-1 expression is rapidly up-regulated on neutrophils after activation and in the same time period that CD62L is shed from the cell surface. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.
- Pathways
- Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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