CD11b Antikörper (APC)

Produktnummer ABIN375391

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch CD11b in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für CD11b Antikörper (APC) (ABIN375391)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD11b Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: M1-70

Produktdetails anti-CD11b Antikörper (APC)

Spezifität: Mouse/Human/Rhesus/Baboon/Rabbit CD11b, Mr 170 kDa

Produktmerkmale: Rat Anti-Mouse CD11b-APC

Aufreinigung: Purified

Immunogen: C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Block - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, and AF488 conjugates 1 g/106 cells PE, APC, SPRD, CY5, PE/CY7, APC/CY7, PACBLU, AF647 and AF700 0.3 g/106 cells conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Kommentare:

In vitro and in vivo blocking

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: 0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Details zu CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung: CD11b

Hintergrund: CD11b (integrin α M subunit) combines with CD18 (integrin β 2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation