XPC Antikörper (C-Term)

Produktnummer ABIN375331

Produktdetails anti-XPC Antikörper

Target: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XPC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: Reacts with human 105 kDa XPC protein

Kreuzreaktivität: Maus

Kreuzreaktivität (Details): Cross reacts with mouse protein due to sequence homology

Aufreinigung: Antiserum

Immunogen: Synthetic peptide derived from Cter domain of human XPC protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/500 - WB : 1/200 to 1/2 000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu XPC

Target: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Andere Bezeichnung: DNA Repair Protein Complementing XP-C Cells (XPC Produkte)

Synonyme: RAD4 antikoerper, XP3 antikoerper, XPCC antikoerper, XPC complex subunit, DNA damage recognition and repair factor antikoerper, xeroderma pigmentosum, complementation group C antikoerper, XPC antikoerper, Xpc antikoerper

Hintergrund: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A.

UniProt: Q01831

Pathways: p53 Signalweg, DNA Reparatur