Ephrin B2 Antikörper (AA 328-332)

Produktnummer ABIN362834

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Ephrin B2 in WB und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte und wurde in 1 Publikation erwähnt.

Kurzübersicht für Ephrin B2 Antikörper (AA 328-332) (ABIN362834)

Target: Ephrin B2 (EFNB2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ephrin B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Ephrin B2 Antikörper

Bindungsspezifität: AA 328-332

Spezifität: The antibody detects endogenous level of total Ephrin-B2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Immunogen: Peptide sequence around AA 328-332 (N-I-Y-Y-K) derived from Human Ephrin B (ephrin-B2) . Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Referenzen für anti-Ephrin B2 Antikörper (ABIN362834)

Toribio, Brown, Novince, Marlow, Hernon, Lanigan, Hildreth, Werbeck, Shu, Lorch, Carlton, Foley, Boyaka, McCauley, Rosol: "The midregion, nuclear localization sequence, and C terminus of PTHrP regulate skeletal development, hematopoiesis, and survival in mice." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 6, pp. 1947-57, (2010) (PubMed).

Details zu Ephrin B2

Target: Ephrin B2 (EFNB2)

Andere Bezeichnung: Ephrin-B2

Hintergrund: Ephrin-B2 encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a lycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.

Molekulargewicht: 37 kDa

NCBI Accession: NP_004084

UniProt: P52799

Pathways: RTK Signalweg, Regulation of Muscle Cell Differentiation