IL4 Receptor Antikörper (Extracellular Domain)

Produktnummer ABIN360908

Der Ratte-Monoklonal Anti-IL4 Receptor-Antikörper wurde für WB validiert. Er ist geeignet zum Nachweis von IL4 Receptor in Proben aus Maus. }

Kurzübersicht für IL4 Receptor Antikörper (Extracellular Domain) (ABIN360908)

Target: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL4 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 16F23

Produktdetails anti-IL4 Receptor Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: This antibody detects IL-4R.

Aufreinigung: Protein A/G affinity chromatography

Immunogen: Recombinant protein of IL-4R extracellular domain.

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IL4 Receptor

Target: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Andere Bezeichnung: CD124 / IL4R

Hintergrund: The Interleukin-4 receptor is a complex consisting of two chains. One chain is the high affinity IL-4 binding (p140, a chain, CD 124) chain and the other chain is the gamma chain. The high affinity IL-4 binding chain belongs to the cytokine receptor superfamily. The cytoplasmic domain contains Ser/Pro-rich regions similar to those present in the IL-2 receptor and GM-CSF receptor ß-chains. The recombinant human IL-4 soluble receptor corresponds to the human IL-4 receptor extracellular domain. The recombinant, human IL-4 sR is a potent IL-4 antagonist. This antibody will block IL-4 binding to its receptor.Synonyms: 582J2.1, IL-4R-alpha, IL4 Receptor alpha, IL4RA, Interleukin-4 receptor alpha chain

Gen-ID: 16190

NCBI Accession: NP_001008700

UniProt: P16382

Pathways: JAK-STAT Signalweg, Positive Regulation of Immune Effector Process