IL4 Receptor Antikörper (C-Term)

Produktnummer ABIN1944783

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-IL4 Receptor Antikörper (Klon RB48074) (ABIN1944783) detektiert spezifisch IL4 Receptor in WB und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL4 Receptor Antikörper (C-Term) (ABIN1944783)

Target: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL4 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: RB48074

Produktdetails anti-IL4 Receptor Antikörper

Bindungsspezifität: AA 677-691, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IL4R antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 677-691 amino acids from the C-terminal region of human IL4R.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-IL4 Receptor Antikörper (ABIN1944783)

Loftus, Kim, Sneddon, Kalush, Brandon, Fuhrmann, Mason, Crosby, Barnstead, Cronin, Deslattes Mays, Cao, Xu, Kang, Mitchell, Eichler, Harris, Venter, Adams: "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q." in: Genomics, Vol. 60, Issue 3, pp. 295-308, (1999) (PubMed).

Details zu IL4 Receptor

Target: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Andere Bezeichnung: IL4R

Hintergrund: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

Molekulargewicht: 89658

Gen-ID: 3566

UniProt: P24394

Pathways: JAK-STAT Signalweg, Positive Regulation of Immune Effector Process