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CD14 Antikörper (N-Term)

Der Maus Monoklonal Anti-CD14-Antikörper wurde für FACS, IP und IHC (fro) validiert. Er ist geeignet, CD14 in Proben von Human und Affe zu detektieren.
Produktnummer ABIN319685

Kurzübersicht für CD14 Antikörper (N-Term) (ABIN319685)

Target

Alle CD14 Antikörper anzeigen
CD14

Reaktivität

  • 302
  • 60
  • 38
  • 26
  • 22
  • 22
  • 22
  • 22
  • 19
  • 19
  • 17
  • 14
  • 14
  • 13
  • 12
  • 9
  • 7
  • 7
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
Human, Affe

Wirt

  • 259
  • 69
  • 38
  • 3
  • 3
  • 1
  • 1
  • 1
Maus

Klonalität

  • 306
  • 66
  • 2
Monoklonal

Konjugat

  • 158
  • 34
  • 25
  • 21
  • 17
  • 10
  • 7
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD14 Antikörper ist unkonjugiert

Applikation

  • 261
  • 124
  • 102
  • 69
  • 62
  • 52
  • 28
  • 24
  • 20
  • 13
  • 12
  • 7
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon

UCHM1
  • Bindungsspezifität

    • 37
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-4, N-Term

    Aufreinigung

    Affinity chromatography on Protein G

    Immunogen

    Human Thymocytes followed by peripheral blood mononuclear cells. Spleen cells from mice immunised with human thymocytes and PBLs were fused with cells from the NS1-Ag4/1 mouse myeloma cell line.

    Isotyp

    IgG2a
  • Applikationshinweise

    Flow cytometry. Immunhistology on frozen sections. Recommended Positive Control: Tonsil. Immunprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    CD14

    Andere Bezeichnung

    CD14

    Hintergrund

    CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

    Gen-ID

    9606

    UniProt

    P08571

    Pathways

    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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