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CD11b Antikörper (FITC)

Name: CD11b Antikörper (FITC)
SKU: ABIN319675
Price: 429.85 EUR
Availability: InStock

ITGAM Reaktivität: Human, Affe FACS Wirt: Maus Monoclonal ICRF44 FITC

(1 reference)

Produktnummer ABIN319675

Datenblatt (PDF)

Target Alle CD11b (ITGAM) Antikörper anzeigen

CD11b (ITGAM) (Integrin alpha M (ITGAM))
Reaktivität
274

177

74

34

20

19

17

14

11

10

7

4

4

2

2

1
Human, Affe
Wirt
157

116

105

2

1

1
Maus
Passende Sekundärantikörper
Klonalität
284

94

2
Monoklonal
Konjugat
125

39

33

29

21

10

8

8

7

7

6

6

5

5

4

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Dieser CD11b Antikörper ist konjugiert mit FITC
Applikation
285

87

86

82

64

49

38

24

23

21

14

14

12

6

5

5

5

4

4

3

2

2

2

2

1

1

1

1
Flow Cytometry (FACS)

Aufreinigung

Affinity Chromatography on Protein G.

Immunogen

Rheumatoid synovial cells and human monocytes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse Sp2/0 myeloma cell line.

Klon

ICRF44

Isotyp

IgG1

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Applikationshinweise

Flow cytometry: neat - 1/10, use 10 μL of the suggested working dilution to label to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.1 mg/mL

Buffer

PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Dilute only prior to immediate use. Avoid cycles of freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Sotiriou, Orlova, Al-Fakhri, Ihanus, Economopoulou, Isermann, Bdeir, Nawroth, Preissner, Gahmberg, Koschinsky, Chavakis: "Lipoprotein(a) in atherosclerotic plaques recruits inflammatory cells through interaction with Mac-1 integrin." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 3, pp. 559-61, (2006) (PubMed).
Target

CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung

CD11b (ITGAM Produkte)

Hintergrund

CD11b is a 165kD molecule also known as the alpha M integrin, MAC-1 and CR3. This molecule is expressed as a heterodimer in association with the beta 2 integrin, and is found upon monocytes, granulocytes, NK cells and some peripheral blood lymphocytes.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor

Gen-ID

3684

NCBI Accession

NP_000623

UniProt

P11215

Pathways

Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation