IRF7 Antikörper (C-Term)

Produktnummer ABIN318754

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IRF7 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für IRF7 Antikörper (C-Term) (ABIN318754)

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IRF7 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects an epitope within the C-terminal of Human Interferon Regulatory Factor 7 (IRF7).

Aufreinigung: Affinity Chromatography.

Immunogen: 14 amino acid peptide sequence near the carboxy terminus of Human IRF7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1.0-2.0 μg/mL. This antibody detects a band of approximately 51 kDa in 293 whole cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IRF7

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Andere Bezeichnung: IRF7

Hintergrund: IRF7 is a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production. Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.Synonyms: IRF-7, Interferon regulatory factor 7

Gen-ID: 3665

NCBI Accession: NP_001563

UniProt: Q92985

Pathways: TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagie