TNF alpha Antikörper

Produktnummer ABIN317259

Der Maus Monoklonal anti-TNF alpha Antikörper (Klon 195) (ABIN317259) detektiert spezifisch TNF alpha in WB, Func und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TNF alpha Antikörper (ABIN317259)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNF alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 195

Produktdetails anti-TNF alpha Antikörper

Produktmerkmale: Synonyms: TNF, TNF-a, TNFA, TNFSF2, Cachectin, Tumor necrosis factor ligand superfamily member 2

Aufreinigung: Purified

Immunogen: Recombinant human tumour necrosis factor alpha produced in Escherichia coli.

Isotyp: IgG3

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on frozen sections. Functional Assays. Immunoblotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Andere Bezeichnung: Tumor Necrosis Factor (TNF-Alpha)

Hintergrund: TNF alpha is a secreted cytokine that induces cell death in a number of tumour cell lines. This antibody does not react with human tumour necrosis factor beta (TNF beta/lymphotoxin). 50 ng of antibody is required to neutralise 1 unit of TNF alpha.Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2

UniProt: P01375

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome